首页>
外国专利>
COMPOSITION CONTAINING AN INHIBITOR OF MYELIN-ASSOCIATED GLYCOPROTEIN (MAG), WHICH CONTAINS A CHANGED OR MUTED FORM OF MAG
COMPOSITION CONTAINING AN INHIBITOR OF MYELIN-ASSOCIATED GLYCOPROTEIN (MAG), WHICH CONTAINS A CHANGED OR MUTED FORM OF MAG
展开▼
机译:包含髓磷脂相关糖蛋白(MAG)抑制剂的组合物,其含有变化或突变形式的MAG
展开▼
页面导航
摘要
著录项
相似文献
摘要
This invention relates to the novel identification of myelin-associated glycoprotein ("MAG") as a potent inhibitor of neural regeneration. More particularly, this invention relates to compositions and methods useful for reversing inhibition of neural regeneration in the central and peripheral nervous system. Assays to monitor the effects of MAG on neural regeneration and to identify agents which will block or promote the inhibitory effects of MAG on neural outgrowth are provided. Screening methods for identifying such agents are also provided. This invention also relates to compositions and methods using agents that can reverse the inhibitory effects of MAG on neural regeneration. Methods for regulating and for promoting neural growth or regeneration in the nervous system, methods for treating injuries or damage to nervous tissue or neurons, and methods for treating neural degeneration associated with disorders or diseases, comprising the step of administering at least one of the compositions according to this invention are provided.
展开▼