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USE OF DENDRITIC CELL-DEPLETED COMPOSITIONS TO IMPROVE THE TRANSPLANTATION OF ALLOGENIC HEMATOPOIETIC CELLS
USE OF DENDRITIC CELL-DEPLETED COMPOSITIONS TO IMPROVE THE TRANSPLANTATION OF ALLOGENIC HEMATOPOIETIC CELLS
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机译:使用树突状细胞缺失的组合物改善同种异体造血细胞的移植
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摘要
Methods of reducing or preventing graft versus host disease in an allogeneic hematopoietic system reconstituting cells transplant recipient comprising administering to the recipient allogeneic hematopoietic system reconstituting cells in which the number of dendritic cells has been effectively reduced, thereby reducing or preventing graft versus host disease, are provided. Also provided are methods of increasing the chance of survival for an allogeneic hematopoietic system reconstituting cells transplant recipient comprising administering to the recipient allogeneic hematopoietic system reconstituting cells in which the number of dendritic cells has been effectively reduced, thereby improving the chance for survival of the recipient. Columns for preparing hematopoietic system reconstituting cells prior to their transplantation are disclosed that provide for the selection of CD34+ cells and the removal of dendritic cell progenitors.
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