Pharmaceutical, nutraceutical, dermatological or cosmetic composition useful for treating diseases or esthetic problems resulting from apoptosis comprises sesquiterpene lactone

摘要

Pharmaceutical, nutraceutical, dermatological or cosmetic composition comprises a sesquiterpene lactone (I), a derivative or analog of (I) or a (I)-containing plant extract. ACTIVITY : Antiseborrheic; Antiinflammatory; Antiarthritic; Neuroprotective; Antipruritic; Antidiabetic. MECHANISM OF ACTION : Apoptosis inhibitor; Caspase inhibitor. Incubating Jurkat cells with vulgarin (2.6 MicroM) gave 100% inhibition of apoptosis induced by sodium arsenate (5 MicroM).