首页>
外国专利>
Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin D derivative
Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin D derivative
展开▼
机译:通过预先服用维生素D衍生物增加阿仑膦酸盐或其他双膦酸盐的生物利用度的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides a method of increasing the bioavailability of a bis-phosphonate comprising administering an effective predose of a vitamin D derivative, such as alphacalcidol or calcitriol, and after a time interval, administering a therapeutic dose of bis-phosphonate, such as alendronate. The present invention also relates to the use of vitamin D derivatives and bisphosphonates for the manufacture of medicaments for treating osteoporosis, metastatic bone disease, and Paget's disease.
展开▼