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LACTIC ACID-PRODUCING YEAST AND LACTIC ACID PRODUCING METHOD

机译:乳酸生产酵母和乳酸生产方法

摘要

PROBLEM TO BE SOLVED: To construct a system for highly expressing lactic acid, desirable for producing the lactic acid in a yeast.;SOLUTION: The yeast comprising a lactic acid producing yeast is provided, wherein pyruvate decarboxylase activity and alcohol dehydrogenase activity are each decreased in the yeast and a DNA which encodes a protein having lactate dehydrogenase activity is given to the yeast so as to be expressible. It is preferable that a pyruvate decarboxylase gene is destroyed in the organic acid-producing yeast. Further, it is preferable that an alcohol dehydrogenase gene is destroyed therein.;COPYRIGHT: (C)2006,JPO&NCIPI
机译:解决的问题:构建高表达乳酸的系统,该系统是在酵母中产生乳酸的理想方法。解决方案:提供了一种包含产生乳酸的酵母的酵母,其中丙酮酸脱羧酶活性和醇脱氢酶活性均降低在酵母中将其表达,然后将编码具有乳酸脱氢酶活性的蛋白质的DNA提供给酵母以使其可表达。丙酮酸脱羧酶基因优选在产生有机酸的酵母中被破坏。此外,优选其中的醇脱氢酶基因被破坏。;版权所有:(C)2006,JPO&NCIPI

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