IMMUNOLOGICAL COMPETENT CELL-ORIENTED OLIGONUCLEOTIDE LIPOSOME COMPLEX

摘要

PROBLEM TO BE SOLVED: To provide an oligonucleotide liposome complex capable of being specifically delivering oligonucleotide to an immunological competent cell by intravenous administration.;SOLUTION: The oligonucleotide liposome complex comprises a liposome containing at least one kind of sugar lipid selected from a group consisting of cholesten-5-yloxy-N-(4-((1-imino-2-β-D-thiomanosyl-ethyl)amino)alkyl)formamide and cholesten-5-yloxy-N-(4-((1-imino-2-β-D-thiofucosyl-ethyl)amino)alkyl)formamide, and an oligonucleotide.;COPYRIGHT: (C)2006,JPO&NCIPI