TECHNIQUE FOR EFFICIENTLY VISUALIZING LARGE-SCALE PROTEIN INTERACTION DATA

摘要

PPROBLEM TO BE SOLVED: To provide a technique for visualizing a protein interaction network in a clear three-dimensional graph excellent in terms of beauty. PSOLUTION: This method for efficiently visualizing large-scale protein interaction data is related to a technique for generating a three-dimensional graph formed by visualizing large-scale protein interaction data, and is characterized by comprising: a first step for producing an initial layout by placing all nodes of protein interaction data on the surface of a sphere by increasing both horizontal and vertical angles of polar coordinates; and a second step for creating a graph by repeating a process moving each node of the initial layout to an equilibrium position considering global spring forces between non-adjacent nodes as well as local spring forces between adjacent nodes on a predetermined number of times. The method is much faster than the conventional algorithms, can be used for interactive analysis, as well as provide an integrated system capable of directly visualizing inquiry results of a database. PCOPYRIGHT: (C)2006,JPO&NCIPI