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METHOD FOR INTRODUCING DRUG AND APPARATUS FOR INTRODUCING DRUG

机译:药物引入方法和药物引入装置

摘要

PROBLEM TO BE SOLVED: To provide a method for introducing a drug by which the drug can selectively be introduced into a specific cell with an inexpensive apparatus and to provide the apparatus for introducing the drug.;SOLUTION: The drug such as a therapeutic gene is injected into a biological tissue with a syringe to localize the drug near the cell into which the drug is to be introduced. A pigment (e.g. hemoglobin) as a target near the cell is irradiated with laser beams at ≥100 ps pulse width to thereby introduce the drug into the cell. The laser pulse is selectively absorbed with the pigment (linear absorption) to induce a temperature rise and a pressure wave (a thermoelastic wave). Thereby, permeability into the cell membrane is increased.;COPYRIGHT: (C)2006,JPO&NCIPI
机译:解决的问题:提供一种用于引入药物的方法,通过该方法可以用廉价的装置将药物选择性地引入特定细胞中,并提供用于引入药物的装置。用注射器将其注射到生物组织中以将药物定位在将要引入药物的细胞附近。用约100 ps脉冲宽度的激光束照射作为细胞附近目标的色素(例如血红蛋白),从而将药物引入细胞。激光脉冲被颜料选择性地吸收(线性吸收)以引起温度上升和压力波(热弹性波)。从而增加了细胞膜的通透性。版权所有:(C)2006,JPO&NCIPI

著录项

  • 公开/公告号JP2005330194A

    专利类型

  • 公开/公告日2005-12-02

    原文格式PDF

  • 申请/专利权人 KEIO GIJUKU;

    申请/专利号JP20040147971

  • 申请日2004-05-18

  • 分类号A61K48/00;A61P43/00;C12M1/00;C12N13/00;C12N15/09;

  • 国家 JP

  • 入库时间 2022-08-21 21:52:08

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