Film-coated tablets containing red grape leaf extract

摘要

The invention relates to a film coated tablet comprising the following constituents: a) at least 50 % by weight of a dried extract of red vine leaves, which is obtainable by extraction of red vine leaves with water and drying; b) up to 50 % by weight of an excipient consisting essentially of at least one binder, at least one disintegrant, at least one filler, and a lubricant; and c) a tablet film consisting essentially of a film former, a plastiziser, a coating agent and optionally a coloring agent.Furthermore, the invention relates to an aqueous extract of red vine leaves is obtainable by a method comprising the steps of: a) collecting red vine leaves at a point of time when the content in flavonoids has reached an optimum; b) drying and crushing the leaves; c) cutting the leaves to pieces; d) extracting the leaves with water at elevated temperatures for 6 to 10 hours; e) concentrating and drying the obtained extract, andaddition of up to 10 % by weight of a flow regulator during the relating to the final total amount of the resulting extract during the drying process (e).