Fluorescence energy transfer and intramolecular energy transfer in the particles using novel compounds

摘要

(57) and method for particle visualization or detection of an analyte comprising a nucleic acid using an intramolecular energy transfer or [summary] fluorescence energy transfer. It contains as a first component, donor energy, as a second component a fluorescent dye is contained in the position each other is the energy exchange distance within the particle, the present application, the Stokes shift of 50nm over the two components and the claims have and also discloses particles protein comprising a ligand analog proteins, polypeptides, nucleic acids, or nucleotides, is attached on the surface of the particles. Further provided is a novel fluorochrome for incorporation into the particles, or useful for the labeling of various nucleic acid molecules, proteins, polypeptides, and nucleotides. Discloses a hybrid phthalocyanine derivatives and phthalocyanine derivatives many new, the present invention has the following claims. The derivatives of these, and may be those containing an electron transfer subunit. may be covalently bonded to the metal to axial ligand is contained in the hybrid phthalocyanine. The present invention is directed to the claims as well as the fluorescence energy transfer compounds, many compounds capable of intramolecular energy transfer further.