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Use of cytochrome p450 enzyme cyp2w1 as a drug target for cancer theraphy

机译:细胞色素p450酶cyp2w1作为癌症治疗的药物靶标的用途

摘要

The present invention relates to a novel drug target in cancer therapy. More closely it relates to use of the cytochrome P450 enzyme CYP2W1 and its promoter as a drug target for cancer therapy. It also relates to screening methods for obtaining therapeutic agents for cancer therapy and to therapeutic agents comprising moieties showing binding affinity for CYP2W1 and moieties with cytotoxic/anti-cancer effect.
机译:本发明涉及癌症治疗中的新型药物靶。更紧密地涉及细胞色素P450酶CYP2W1及其启动子作为癌症治疗的药物靶标的用途。它还涉及用于获得用于癌症治疗的治疗剂的筛选方法,并且涉及包含对CYP2W1表现出结合亲和力的部分和具有细胞毒性/抗癌作用的部分的治疗剂。

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