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Serine/threonine hydrolase proteins and screening assays
Serine/threonine hydrolase proteins and screening assays
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机译:丝氨酸/苏氨酸水解酶蛋白和筛选测定
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摘要
Proteins specific for prostate epithelial cells, normal or neoplastic, are identified and used for diagnosis, development of antibodies, and for evaluating drugs that react with the neoplastic specific proteins. Affinity based probes are used that react specifically with the active site to provide a measure of the enzyme activity of the cells. Prostate epithelial neoplastic cells can be used in screening candidate drugs for their effect in changing the proteome profile as to the serine-threonine hydrolase enzymes, using the affinity based probes for determining the profile.
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