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Microemulsion concentrate for oral administration of water-insoluble anti-cold drug and method for preparing same
Microemulsion concentrate for oral administration of water-insoluble anti-cold drug and method for preparing same
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机译:用于水不溶性抗感冒药的口服微乳浓缩物及其制备方法
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摘要
A microemulsion concentrate comprising a water-insoluble anti-cold drug, a surfactant and an oil, which is prepared by a method comprising: (a) dissolving the water-insoluble anti-cold drug in a co-surfactant to obtain a homogeneous drug solution; (b) adding the surfactant and the oil in the drug solution to obtain a microemulsion pre-concentrate; and (c) removing the co-surfactant from the pre-concentrate, contains emulsified drug microparticles which are stable toward pH change and therefore, provides improved bioavaiability of the drug when orally administered.
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