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Quinolines as allosteric enhancers of the GABAB receptors

机译：喹啉作为GABAB受体的变构增强剂

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摘要

The present invention relates to compounds of formula I embedded image

wherein R¹to R⁶are as described herein, which compounds are active at the GABA_Breceptor and can be used for the preparation of medicaments useful in the treatment of CNS disorders comprising anxiety and depression.

机译：本发明涉及式I化合物 <图像alt =“嵌入式图像” file =“ US20060094754A1-20060504-C00001.GIF” he =“ 38.69mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 58.08mm“ /> 其中R ^{1 至R ^{6 如本文所述，哪些化合物对GABA _{B 受体具有活性，可用于制备药物可用于治疗包括焦虑和抑郁症的中枢神经系统疾病。}}}

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公开/公告号US2006094754A1

专利类型
公开/公告日2006-05-04

原文格式PDF
申请/专利权人 PARICHEHR MALHERBE;RAFFAELLO MASCIADRI;ROGER DAVID NORCROSS;HASANE RATNI;ANDREW WILLIAM THOMAS;
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申请/专利号US20050259860
发明设计人 PARICHEHR MALHERBE;RAFFAELLO MASCIADRI;ROGER DAVID NORCROSS;HASANE RATNI;ANDREW WILLIAM THOMAS;
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申请日2005-10-27
分类号A61K31/47;C07D215/38;
国家 US
入库时间 2022-08-21 21:45:12

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