Process for generating pivaloylacetate esters via carbonylation of chloropinacolone

摘要

Pivaloylacetate esters (1) are a useful intermediates for producing chemicals for use in photographic and xerographic reproduction processes. Such esters can be generated by contacting chloropinacolone (2) with CO, an alcohol of formula R¹OH, and a base in the presence of a catalyst comprising a source of palladium and certain coordinating trisubstituted phosphines of formula (R³)₃P.