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N-but-3-enyl norbuprenorphine and its use as analgesic

机译:N-丁-3-烯基降丁丙诺啡及其镇痛剂用途

摘要

The present invention provides compound having the structure: and pharmaceutically acceptable salts or derivatives thereof, as well as compositions including such compounds. The invention also provides methods of (1) preventing pain, (2) treating pain, (3) inducing sedation, (4) treating opiate addiction, (5) treating opiate withdrawal (abstinence syndrome) and/or (6) treating cough in a patient in need thereof by administering a compound or composition of the invention. embedded image
机译:本发明提供了具有以下结构的化合物及其药学上可接受的盐或衍生物,以及包括这种化合物的组合物。本发明还提供以下方法:(1)预防疼痛,(2)治疗疼痛,(3)诱导镇静,(4)治疗鸦片成瘾,(5)治疗鸦片戒断(戒断综合症)和/或(6)治疗咳嗽。通过施用本发明的化合物或组合物来治疗有需要的患者。 <图像alt =“嵌入式图像” file =“ US07125884-20061024-C00001.GIF” he =“ 42.33mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 45.80mm“ />

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