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P53 binding protein-related protein in cardiomyopathy
P53 binding protein-related protein in cardiomyopathy
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机译:心肌病中P53结合蛋白相关蛋白
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摘要
The present invention is directed to a mouse model of dilated cardiomyopathy in which animals are deficient in the expression of a gene encoding a p53 binding protein-related protein (PRP). The invention also encompasses the mouse PRP gene and protein themselves as well as counterparts found in the human. The various genes and proteins can be used in making transgenic animals and in assays designed to determine the likelihood of an individual developing cardiomyopathy.
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