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Water-soluble polymeric bone-targeting drug delivery system
Water-soluble polymeric bone-targeting drug delivery system
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机译:水溶性高分子靶向骨给药系统
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摘要
The present invention provides bone-targeting polymeric drug delivery systems based on HPMA and related copolymers and methods of making thereof. The water-soluble bone-targeting polymeric conjugates of the present invention comprise water-soluble copolymer backbones (P) which are linked, via a first spacer (S1), with a bone-related therapeutic agents or drug (D) and, via a second spacer (S2), with a bone-targeting moiety (T).
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