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Process for preparing simvastatin having controlled ranges of simvastatin dimer content
Process for preparing simvastatin having controlled ranges of simvastatin dimer content
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机译:具有控制范围的辛伐他汀二聚体含量的辛伐他汀的制备方法
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摘要
The present invention relates to a process for preparing simvastatin, wherein the simvastatin dimer content is controlled. More particularly, the present invention relates to a process for preparing simvastatin having a simvastatin dimer content of about 0.2 to about 0.4% wt. The present invention also relates to a process for preparing simvastatin having a simvastatin dimer content of less than about 0.2% wt. The present invention also discloses a commercial scale process of preparing simvastatin having a specified simvastatin dimer content which is reproducible.
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