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Pharmaceutical composition containing polypeptide Fragments of serralisinas

机译:含有锯缘青蟹多肽片段的药物组合物

摘要

This is related to a composition capable of inhibiting the growth of tumor cells of different Histological origin and activated endothelial cells.The Components of the composition are Fragments of serralisinas polypeptides corresponding to the c-terminal fragment, from methionine within the sequence until the end of the Molecule, which can optionally be combined among themselves and with prodigiosinas that enhance the e Anti tumor effect of the composition.The prodigiosinas in Composition may be a concentration of 0.1-100 nm. The Anti proliferative Action of the composition is mediated by apoptotic mechanisms. His Administration has Antitumor effect in vivo, antiangiogenic and Protector against malignant tumors.
机译:这涉及能够抑制不同组织学来源的肿瘤细胞和活化的内皮细胞生长的组合物。该组合物的成分是与s-末端片段相对应的锯齿藻属多肽的片段,从该序列中的甲硫氨酸直到其末端。分子,可以任选地在它们之间以及与增强组合物的抗肿瘤作用的pro虫组合。组合物中pro虫的浓度可以为0.1-100nm。该组合物的抗增殖作用是通过凋亡机制介导的。他的管理具有体内抗肿瘤作用,抗血管生成和抗恶性肿瘤的保护作用。

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