Constructive improvement introduced in coronary stent coated with biodegradable polymer with a restenosis inhibiting drugs

摘要

"Constructive improvement introduced in coronary stent coated with polu00ecmero biodegradable with medication inhibiting restenosis".With the differential that present a refinement in the PON to view of the spectrum of the structure of the stent perfected (), which is made from a tube of stainless steel.Specification L SS316, which permits, through studies of finite element analysis, the implementation of a cut design, which leads to the formation of a structure with a high potential for concentration.With the great power of flexibility and adding even high reliability as its resistance to structural stress, caused due to concentration of stress in areas subject to torsion.Such design obtained is composed of circumferential bands with hollow structures (A1) around the contour of a nominal diameter for that band.Where the union between two of these bands is by elements of the type laminasde connection (A2), arranged in an alternating between themselves, and the structures castings (A1),They show profile curvature (A3), minimizing the interference of the stent improved (a) with the interior of the coronary artery.Where the union between two or more structures castings (A1) or between the latter and the elements of the type blades of connection (A2), is the continuity of the stainless steel.Without the need for amendments of the type solders, allowing areas of inflection (A4) and (A5) are highly resistant to damage by the stress of the material.In addition, the request now claimed builds within the spectrum of the medium for elution (b), the use of a biodegradable polymer.Which in essence provides a composition with the polymers poly L - lactide, 50 / 50 poly DL - lactide - co glycolide, 75 / 25 poly lactide, L - co - caprolactone) and poly vinyl pyrrolidone,In four distinct layers of loading of the medication inhibiting restenosis (c).