首页> 外国专利> Methods to cultivate cells immortalized by E1 sequences of adenovu00ecrus and to produce a product in cells immortalized by the sequences of adenovu00ecrus E1, and.Culture of cells immortalized by the sequences of adenovu00ecrus E1

Methods to cultivate cells immortalized by E1 sequences of adenovu00ecrus and to produce a product in cells immortalized by the sequences of adenovu00ecrus E1, and.Culture of cells immortalized by the sequences of adenovu00ecrus E1

机译:培养由adenov u00ecrus的E1序列永生的细胞并在由adenov u00ecrus E1的序列永生的细胞中产生产物的方法,以及由adenov u00ecrus E1的序列永生的细胞的培养。

摘要

Methods to cultivate cells immortalized by E1 sequences of adenovu00ecrus and to produce a product in cells immortalized by the sequences of adenovu00ecrus E1, and.Culture of cells immortalized by E1 sequences of adenovu00ecrus ".The invention provides procedures for cultivating cells derived from embryonic cells of retinoblasto by E1 sequences of adenovirus, preferably cells per.C6u00ac tmu00ac, to improve the income of the product of such cells.Feeding strategies are offered for such cells and cultures with very high cell densities, resulting in high yields of products, such as recombinant antibodies.
机译:培养由阿德诺夫E1序列永生的细胞并在由阿德诺夫E1序列永生的细胞中产生产物的方法和培养由阿德诺夫E1序列永生的细胞的方法。本发明提供了用于通过腺病毒的E1序列培养成视网膜细胞胚细胞的细胞,最好是每C6 u00ac tm u00ac的细胞,以提高此类细胞产物的收益。提供此类细胞和高密度细胞培养物的饲养策略,导致高产量的产品,例如重组抗体。

著录项

  • 公开/公告号BRPI0409895A

    专利类型

  • 公开/公告日2006-05-23

    原文格式PDF

  • 申请/专利权人 CRUCELL HOLLAND B.V.;

    申请/专利号BR2004PI09895

  • 发明设计人 CHRISTOPHER ADAM YALLOP;

    申请日2004-05-06

  • 分类号C12N5/10;

  • 国家 BR

  • 入库时间 2022-08-21 21:40:08

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