prognosis for hematologic malignancy

摘要

"PROGNOSTIC FOR HEMATOLOGICAL MALIGNITY". The present invention relates to methods for treating cancer patients, and preferably hematologic malignancy, including analyzing gene expression profiles and / or molecular markers of a patient to determine the patient's situation and / or prognosis. The invention also relates to methods for analyzing whether a non-incident or non-resistant patient is capable of responding to treatment with farnesyl transferase inhibitors (FTIs) and optionally other therapeutic agents. The methods are also useful for monitoring patient therapy and selecting a course of therapy. Modulated genes in response to FTI treatment are provided and are used in profiling.