PURIFICATION OF DNA BY FORMATION OF A TRIPLE HELIX WITH IMMOBILISED OLIGONUCLEOTIDE

摘要

A novel method for purifying double stranded (ds) DNA comprises passing a mixt. contg. the DNA in soln. over a support to which an oligonucleotide (ON) is covalently attached, where the ON is able to form a triple helix by hybridisation with a specific sequence (I) present in the DNA.