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DIAGNOSIS AND TREATMENT OF LIVER, PULMONARY AND CARDIAC FIBROSIS
DIAGNOSIS AND TREATMENT OF LIVER, PULMONARY AND CARDIAC FIBROSIS
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机译:肝,肺和心脏纤维化的诊断和治疗
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摘要
This application is directed to a method for the treatment of fibrosis, preferably liver fibrosis, pulmonary fibrosis and cardiac fibrosis, in a subject in need of such treatment comprising administering to said subject an amount of an inhibitor of HNOEL-iso polypeptide sufficient to effect a substantial inhibition of the HNOEL-iso polypeptide so as to thereby treat the subject. This application is also directed to a process of obtaining a compound which inhibits human HNOEL-iso polypeptide. This application is also directed to use of a compound identified by that process in the preparation of a medicament for therapy of disease, in particular fibrosis, and to diagnostic aspects related to HNOEL-iso polypeptide.
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