首页> 外国专利> PHARMACEUTICAL COMPOSITIONS AND KITS CONTAINING A HEPATITIS C VIRUS NS3/4A PROTEASE INHIBITOR AND CYTOCHROME P450 MONOOXYGENASE INHIBITOR

PHARMACEUTICAL COMPOSITIONS AND KITS CONTAINING A HEPATITIS C VIRUS NS3/4A PROTEASE INHIBITOR AND CYTOCHROME P450 MONOOXYGENASE INHIBITOR

机译:包含丙型肝炎病毒NS3 / 4A蛋白酶抑制剂和细胞色素P450单氧合酶抑制剂的药物组合物和药盒

摘要

The present invention relates to co-administering a Hepatitis C virus NS3/4A protease inhibitor and a cytochrome P450 monooxygenase inhibitor. The combination acts by interfering with the life cycle of the hepatitis C virus and is therefore useful as an antiviral therapy. As such, the combination may be used for treating or preventing Hepatitis C infections in patients. The invention also relates to compositions comprising the combination of inhibitors. The invention also relates to kits and pharmaceutical packs comprising a Hepatitis C virus NS3/4A protease inhibitor and a cytochrome P450 monooxygenase inhibitor. The invention also relates to processes for preparing these compositions, combinations, kits, and packs.
机译:本发明涉及共同施用丙型肝炎病毒NS3 / 4A蛋白酶抑制剂和细胞色素P450单加氧酶抑制剂。该组合通过干扰丙型肝炎病毒的生命周期发挥作用,因此可用作抗病毒治疗。这样,该组合可以用于治疗或预防患者的丙型肝炎感染。本发明还涉及包含抑制剂组合的组合物。本发明还涉及包含丙型肝炎病毒NS3 / 4A蛋白酶抑制剂和细胞色素P450单加氧酶抑制剂的试剂盒和药物包装。本发明还涉及制备这些组合物,组合,药盒和包装的方法。

著录项

  • 公开/公告号IL175211D0

    专利类型

  • 公开/公告日2006-09-05

    原文格式PDF

  • 申请/专利权人 VERTEX PHARMACEUTICALS INCORPORATED;

    申请/专利号IL20060175211

  • 发明设计人

    申请日2006-04-26

  • 分类号A61K;A61K31/7056;A61K38/21;A61K45;A61K45/06;

  • 国家 IL

  • 入库时间 2022-08-21 21:39:04

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