MYCOBACTERIUM TUBERCULOSIS SPECIFIC PROTEIN AND GENE, AND ITS APPLICATIONS

摘要

The gene represented by open reading frame Rv388lc of M. tuberculosis has been sequenced and the sequence of the protein encoded by this gene deduced. The DNAs and -their encoded polypeptides can be used for vaccines. Combinations of this gene in different vectors including naked DNA, live attenuated poxvirus and live M. bovis BCG can be used for improved vaccines for bacterial pathogens and parasites.