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cathepsin k inhibitor combinations and a bisphophonate used in the treatment of bone metastases, tumor growth and tumor induced bone loss

机译:组织蛋白酶k抑制剂组合和双膦酸酯用于治疗骨转移,肿瘤生长和肿瘤诱导的骨丢失

摘要

"the combination of an inhibitor of cathepsin k and bisphosphonate therapy in the treatment of bone metastase to development of cancer cells and the bone loss induced by a tumor, the present invention relates to pharmaceutical preparations comprising certain types of b isphosphonates and certain types of cathepsin k inhibitors.especially in the prevention and treatment of bone metastases and hypercalcemia induced by a tumor, tumor development, tumor induced bone loss and bone loss caused by diseases such as osteoporosis, bone loss due ite in anticancer therapy.
机译:组织蛋白酶k抑制剂和双膦酸盐疗法在治疗骨转移到癌细胞的发展和由肿瘤引起的骨损失中的组合,本发明涉及药物制剂,其包含某些类型的β-膦酸酯和某些类型的β-膦酸酯。组织蛋白酶k抑制剂。特别是在预防和治疗由肿瘤引起的骨转移和高钙血症,肿瘤发展,肿瘤引起的骨质流失以及由骨质疏松症,因ITE引起的骨质流失等疾病引起的骨质流失。

著录项

  • 公开/公告号MA27925A1

    专利类型

  • 公开/公告日2006-06-01

    原文格式PDF

  • 申请/专利权人 NOVARTIS AG.;

    申请/专利号MA20060028737

  • 发明设计人 ZIMMERMANN JOHANN;GOESSL CARSTEN;

    申请日2006-01-18

  • 分类号A61K31/663;A61K31/451;A61K31/495;A61K31/505;A61P19/00;A61P35/00;

  • 国家 MA

  • 入库时间 2022-08-21 21:38:36

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