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INHIBITION OF FGFR3 AND TREATMENT OF MULTIPLE MYELOMA.
INHIBITION OF FGFR3 AND TREATMENT OF MULTIPLE MYELOMA.
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机译:FGFR3的抑制和多发性骨髓瘤的治疗。
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摘要
Methods of inhibiting fibroblast growth factor receptor 3 and treating various conditions mediated by fibroblast growth factor receptor 3 are provided that include administering to a subject a compound of Structure I, a pharmaceutically acceptable salt thereof, a tautomer thereof, or a pharmaceutically acceptable salt of the tautomer. Compounds having the Structure I have the following structure where and have the variables described herein. Such compounds may be used to prepare medicaments for use in inhibiting fibroblast growth factor receptor 3 and for use in treating conditions mediated by fibroblast growth factor receptor 3 such as multiple myeloma.
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