首页> 外国专利> (2R, 3R, 4S, 5R, R R 2 ', 3', 4 ', 5' - (S) - 2,2 '- ciclohexanodiilbis trans - 1,4 - imino (2 - {2 - (1 - methyl - 1H imidazole - 4-yl) ethyl amino} - 9h purin - 6.9 - diyl) bis 4 - (2 - Ethyl 2h-tetrazol-5-yl) - tetrahydro - 3.4 furanodiol as A2A agonist

(2R, 3R, 4S, 5R, R R 2 ', 3', 4 ', 5' - (S) - 2,2 '- ciclohexanodiilbis trans - 1,4 - imino (2 - {2 - (1 - methyl - 1H imidazole - 4-yl) ethyl amino} - 9h purin - 6.9 - diyl) bis 4 - (2 - Ethyl 2h-tetrazol-5-yl) - tetrahydro - 3.4 furanodiol as A2A agonist

机译:(2R,3R,4S,5R,RR 2',3',4',5'-(S)-2,2'-环己二腈反式-1,4-[亚氨基(2-{[2-(1-甲基-1H咪唑-4-基)乙基]氨基]-9h嘌呤-6.9-二基)]双[4-(2-乙基2h-四唑-5-基)-四氢-3.4呋喃二醇]作为A2A激动剂

摘要

Refers to Salts and solvates of (2R, 3R, 4S, 5R, R R 2 ', 3', 4 ', 5' - (S) - 2,2 '- ciclohexanodiilbis trans - 1,4 - [imino (2 - {[2 - (1 - methyl - 4 - il - 1H imidazole) ethyl] amino} - 9h purin - 6.9 - diyl)] bis [4 - (2 - Ethyl 2h-tetrazol-5-yl) - tetrahydro - 3.4 furanodiol] and a preparation method. It also relates to a Pharmaceutical composition.This Compound is a potent agonist of adenosine receptor A2a, useful in the treatment of inflammatory diseases such as Asthma and chronic obstructive pulmonary disease
机译:指(2R,3R,4S,5R,RR 2',3',4',5'-(S)-2,2'-环己二腈反式-1,4-[亚氨基(2-{ [2-(1-甲基-1-4--1H咪唑)乙基]氨基}-9h嘌呤-6.9-二基)]双[4-(2-乙基2h-四唑-5-基)-四氢-3.4呋喃二醇]该化合物是一种有效的腺苷受体A2a激动剂,可用于治疗炎症性疾病,如哮喘和慢性阻塞性肺疾病

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