Saliciltiazoles replaced with Diphenylamine DIPHENYLAMINE derivatives as inhibitors of the phosphotyrosine phosphatase 1b and processes for their Preparation

摘要

Referring to a saliciltiazol derived Compound of formula I, wherein R1, R2, R3, R4 and R5 are h, F, Oh, CF3, among others; R6 is H, alkyl of C1 - C6; is a Link, CH2, NH, S, among others; b is NH, NH alkyl C1 C4 -, NH (CO); d is phenyl Heterocycles. It also relates to a Medicine and a preparation method of the Medicine.This Compound is an inhibitor of the phosphotyrosine phosphatase 1b and is helpful to reduce the level of blood glucose