首页> 外国专利> Pharmaceutical compound with the effect on the growth and the mineralization of osseous-skeleton system and on mature years bone and cartilage diseases among humans and animals, and method for its application

Pharmaceutical compound with the effect on the growth and the mineralization of osseous-skeleton system and on mature years bone and cartilage diseases among humans and animals, and method for its application

机译:对骨-骨骼系统的生长和矿化以及对人畜动物骨骼和软骨疾病有影响的药物化合物及其应用方法

摘要

The invention dissolves the problem of the pharmaceutical preparation affecting the processes of the growth and the mineralisation of the osteo-skeletal system in the physiology and in the osteochondropathy in the matured people and animals. The essence of the invention is that 3-hydroxy-3-methylbutyrate (HMB) and its derivatives such keto-isokaproic acid (KIC) and leucin and isoleucine are used as chemical compound in a dose 0.001-1 g/kg/day, alone or in combination with alpha-ketoglutarate (AKG) or/and glutamines or/and glutamate or/and alpha- ketoglutarate of ornithine or/and dipeptides of glutamine and other amino acids or/and tripeptides of glutamine and other amino acids or/and di- and tripeptides of glutamate with other amino acid, or/and mono- and bivalent metal salts and other alpha-keto of glutarate or/and glutamine or/and glutamate or/and ornithine of alpha-ketoglutarate, in a dose 0.001-1 g/kg/day for producing of the curative preparation, functional and medical food.
机译:本发明解决了药物制剂影响成熟的人和动物的生理和骨软骨病的生长和矿化的骨骼-骨骼系统的问题。本发明的实质是单独使用0.001-1g / kg /天的剂量的3-羟基-3-甲基丁酸(HMB)及其衍生物,例如酮-异己酸(KIC)和亮氨酸和异亮氨酸作为化合物。或与α-酮戊二酸(AKG)或/和谷氨酰胺或/和谷氨酸或/和鸟氨酸的α-酮戊二酸或/和谷氨酰胺和其他氨基酸的二肽或/和谷氨酰胺和其他氨基酸的三肽或/和di -谷氨酸与其他氨基酸的三肽,或/和一价或二价金属盐以及谷氨酸或/和谷氨酰胺或/和谷氨酸或/和鸟氨酸的其他α-酮,剂量为0.001-1 g / kg / day用于生产治疗性制剂,功能性和医疗食品。

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