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A family of genes that encode apoptosis-related, peptide-encoded peptides and methods for their use
A family of genes that encode apoptosis-related, peptide-encoded peptides and methods for their use
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机译:编码凋亡相关肽编码肽的基因家族及其使用方法
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摘要
An isolated polynucleotide at least 60% homologous to SEQ ID NO: 1, 3, 5 or 18 encoding a SARP polypeptide; vectors comprising a polynucleotide sequence encoding at least 11 consecutive amino acids of alphaSARP polypeptide; a host cell transformed with an isolated polynucleotide or vector; antibodies specific for SARP and use of such polynucleotides and antibodies in diagnostic and therapeutic method. Therapeutic uses of antibodies and polynucleotides of sarp. Methods for treating diseases related to the regulation of SARP expression in tissue and bodily fluid samples, including cancers.
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机译:与编码SARP多肽的SEQ ID NO:1、3、5或18至少60%同源的分离的多核苷酸;载体,其包含编码αSARP多肽的至少11个连续氨基酸的多核苷酸序列;用分离的多核苷酸或载体转化的宿主细胞; SARP特异的抗体以及此类多核苷酸和抗体在诊断和治疗方法中的用途。抗体和sarp多核苷酸的治疗用途。治疗与调节组织和体液样本中SARP表达有关的疾病的方法,包括癌症。
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