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LIPOPOLYSACCHARIDE (LPS) EXTRACTED FROM ESCHERICHIA COLI

机译:大肠埃希氏菌提取的脂多糖

摘要

The invention relates to lipopolysaccharides extracted from E. coli DSM 6601. This LPS differs from the known LPS extracted from E. coli in particular with regard to the phosphorylated sugar moiety of the core and to the degree of polymerization of the O-chain. The A lipoid corresponds structurally and biologically to the classic type of E. coli. The inventive LPS is not only suitable for identifying the coli strain which carries it, but also provides the latter with a reduced pathogenic capability, whilst retaining its immunomodulative effect.
机译:本发明涉及从大肠杆菌DSM 6601中提取的脂多糖。该LPS与已知的从大肠杆菌中提取的LPS不同,特别是在核心的磷酸化糖部分和O链的聚合度方面。类脂A在结构和生物学上对应于经典类型的大肠杆菌。本发明的LPS不仅适合于鉴定携带它的大肠杆菌菌株,而且还为后者提供了降低的致病能力,同时保留了其免疫调节作用。

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