HUMAN, NUTRIFICALLY SPECIFIC SUPPRESSOR PROTEIN, FOR THE PROTEIN CODING POLYNUCLEOTIDE, CELL TRANSFORMED WITH THE POLYNUCLEOTIDE, AND METHOD FOR SUPPRESSING THE PROLIFERATION OF CANCER CELLS USING THE EXPRESSION VECTOR

摘要

The present invention provides a human tumor suppressor protein having the amino acid sequence of SEQ ID NO: 2; a polynucleotide encoding the tumor suppressor protein; an expression vector containing the polynucleotide; a microorganism or animal cell transformed with the expression vector; a method for suppressing proliferation of a cancer cell which comprises introducing the expression vector into a cancer cell to induce apoptosis thereof; and a pharmaceutical composition for preventing or treating cancer which comprises a therapeutically effective amount of the polynucleotide and a pharmaceutically acceptable carrier.