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USEFUL PHENOXIALQUILAMINE DERIVATIVES AS AGONISTS OF DELTA OPIOID RECEIVER.

机译:有用的苯甲醛奎明胺衍生物作为三角洲阿片类药物受体的激动剂。

摘要

A compound represented by the following general formula (I), or one of its salts: in which, X represents the following group (II), (III), (IV), (V) or (VI), A? represents a 6-membered carbocyclic group, saturated or unsaturated, such as a benzene or cyclohexane ring, or a heterocyclic group, such as a furan ring, in which said group "A" may be substituted by one more substituents selected from the group consisting of a C1-6 alkyl group, a C2-6 alkoxy group, a C2-6 alkenyl group, a halogen atom, a hydroxy group, a cyano group, an amino group, an N, N-di (C alkyl) group C1-6) amino, an N, N-di (substituted C1-6 alkyl) amino group, a nitro group, a carbamoyl group, an N, N-di (C1-6 alkyl) carbamoyl group, an N, N group -di (C1-6 substituted alkyl) carbamoyl, a carboxyl group, a C1-6 alkoxycarbonyl group that may be substituted, or a C1-6 alkylcarbonyl group that may be substituted, ¿B¿ represents -CH2-, -CHOH -, - (C = O) -, - CH2CH2- or a simple link, does n ¿represent 0, 1 or 2.
机译:由以下通式(I)表示的化合物或其盐之一:其中,X代表以下基团(II),(III),(IV),(V)或(VI)。代表饱和或不饱和的6元碳环基团,例如苯或环己烷环,或杂环基团,例如呋喃环,其中所述基团“ A”可以被选自以下的一个或多个取代基取代: C 1-6烷基,C 2-6烷氧基,C 2-6烯基,卤素原子,羟基,氰基,氨基,N,N-二(C烷基)基团C1的定义-6)氨基,N,N-二(取代的C 1-6烷基)氨基,硝基,氨基甲酰基,N,N-二(C 1-6烷基)氨基甲酰基,N,N-双(C 1-6取代的烷基)氨基甲酰基,羧基,可被取代的C 1-6烷氧羰基或可被取代的C 1-6烷基羰基,B代表-CH 2-,-CHOH-,- (C = O)-,-CH2CH2-或简单链接,n代表0、1或2。

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