DERIVATIVES OF ACILAMINOTIAZOL, ITS PREPARATION AND ITS USE IN THERAPEUTICS.

摘要

Compound that responds to the general formula (1): in which: n is equal to 0, 1, 2 or 3; X represents an oxygen or sulfur atom; R1 represents, independently of one another when n = 2 or 3, a halogen, hydroxy, C1-3 alkyl, C1-3 alkoxy, trifluoromethyl, trifluoromethoxy or methylenedioxy atom; R2 represents a C1-6 alkyl group optionally substituted with a C3-7 cycloalkyl group, phenyl, a C1-3 alkoxy group, hydroxy or a halogen atom; a C3-7 cycloalkyl, piperidinyl or phenyl group; the C3-7 cycloalkyl, piperidinyl and phenyl groups being optionally substituted with one or more C1-3 alkyl groups, C1-3 alkoxy, hydroxy or a halogen atom; R3 represents a hydrogen atom or a C1-6 alkyl group optionally substituted with a C3-7 cycloalkyl group; R4 represents a hydrogen atom or a C1-4 alkyl group; R5 and R5 '' represent, independently of each other, a hydrogen atom, hydroxy, a halogen atom, a C1-3 alkyl group; or R5 and R5 "together form an oxo group; and R 6 represents a hydrogen atom, a halogen atom, C 1-3 alkyl, C 1-3 alkoxy, trifluoromethyl, or trifluoromethoxy; in base form, acid, hydrate or solvate addition salt.