MODEL FOR EVALUATING THE EFFICACY OF LOCALLY APPLIED ANTIPROLIFERATIVES OR OTHER AGENTS ON NEOINTIMAL HYPERPLASIA, IMMUNOHISTOCHEMICAL AND VASCULAR CELL CYCLE CHANGES IN BALLOON-INJURED RAT CAROTID ARTERIES

摘要

A methodology for evaluating the efficacy of locally appliedantiproliferatives and/or other therapeutic agents on neointimal hyperplasia,as well as immunohistochemical and vascular cell cycle changes, in balloon-injured rat carotid arteries may be utilized for determining the efficacy oftreatments in humans.