TNF-LIKE WEAK INDUCER OF APOPTOSIS (TWEAK) RECEPTOR BINDING DOMAIN

摘要

The present invention provides the TWEAK receptor and methods for identifyingand using agonists and antagonists of the TWEAK receptor. In particular, theinvention provides methods of screening for agonists and antagonists and fortreating diseases or conditions mediated by angiogenesis, such as solid tumorsand vascular deficiencies of cardiac or peripheral tissue.