THERAPEUTIC AGENT FOR NON-ALCOHOLIC FATTY LIVER DISEASE, AND SCREENING METHOD FOR DRUG CANDIDATE COMPOUND FOR TREATMENT OR PREVENTION OF NON-ALCOHOLIC FATTY LIVER DISEASE

摘要

A therapeutic agent for a non-alcoholic fatty liver disease comprising amelanin-concentrating hormone receptor antagonist as an active ingredient,which is developed based on a novel mechanism of action that a melanin-concentrating hormone receptor is involved in non-alcoholic fatty liverdiseases. A method for screening a drug candidate compound for the treatmentor prevention of a non-alcoholic fatty liver disease by utilizing themechanism.