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Site-specific immunization in order to establish antibodies with specificity for the E7 oncoprotein of high-risk HPVs
Site-specific immunization in order to establish antibodies with specificity for the E7 oncoprotein of high-risk HPVs
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机译:为了建立对高危HPV E7癌蛋白具有特异性的抗体,进行了位点特异性免疫
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摘要
The present invention relates to a method for establishment of antibodies with specificity for high-risk HPVs compared to immunization using the whole antigen of high-risk HPVs, wherein the method includes an exclusion of evolutionary conserved motifs as well as regions with high similarity to E7 proteins of low-risk HPVs, as well as thus obtained antibodies.
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