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ANTIINFLAMMATORY INHIBITORS OF RESPIRATORY BURST IN ADHERENT NEUTROPHILS

机译:粘附性中性粒细胞呼吸爆发的抗炎抑制剂

摘要

The present invention relates to a method of treating an inflammatory disorder in a subject with an effective amount of compound having the general formula (I) as described in the present application, under conditions effective to treat the inflammatory disorder. The present invention also relates to a method of inhibiting respiratory burst in neutrophils without inhibiting degranulation in or bacterial killing by the neutrophils by contacting neutrophils with the compounds described above.
机译:本发明涉及在有效治疗炎症性疾病的条件下,用有效量的本申请所述的通式(I)的化合物治疗对象的炎症性疾病的方法。本发明还涉及通过使嗜中性粒细胞与上述化合物接触而抑制嗜中性粒细胞呼吸爆发而不抑制嗜中性粒细胞脱粒或细菌杀死细菌的方法。

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