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DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH G PROTEIN-COUPLED RECEPTOR KINASE 6 (GRK6)
DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH G PROTEIN-COUPLED RECEPTOR KINASE 6 (GRK6)
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机译:与G蛋白偶联受体激酶6(GRK6)相关的疾病的诊断和治疗
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摘要
The invention provides a human GRK6 which is associated with cardiovascular diseases, cancer, endocrinological diseases, metabolic diseases, gastroenterological diseases, hematological diseases, respiratory diseases, inflammation, muscle skeleton diseases, neurological diseases and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, cancer, endocrinological diseases, metabolic diseases, gastroenterological diseases, hematological diseases, respiratory diseases, inflammation, muscle skeleton diseases, neurological diseases and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of GRK6 as well as pharmaceutical compositions comprising such compounds.
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