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Computer system and method for calculating a pharmacokinetic characteristic of a chemical substance in insects

机译:用于计算昆虫中化学物质的药代动力学特征的计算机系统和方法

摘要

Computer system for calculating a pharmacokinetic behavior of a chemical substance in insects, comprising: ;a physiologically based pharmacokinetic simulation model (102) of an insect for predicting concentration/time profiles of the chemical substance in compartments of the insect, the simulation model having at least one parameter which is dependent on the substance, and ;a prediction module (110) for predicting the at least one parameter on the basis of a physicochemical property of the substance.
机译:用于计算昆虫中化学物质的药代动力学行为的计算机系统,包括:昆虫的基于生理学的药物代谢动力学模拟模型( 102 ),用于预测昆虫体内化学物质的浓度/时间分布。昆虫,该模拟模型具有至少一个依赖于该物质的参数,以及预测模块( 110 ),该预测模块用于基于该物质的物理化学性质来预测该至少一个参数。

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