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MULTI-RING COMPOUNDS FOR REGULATING GUT MOTILITY, FOOD INTAKE, AND WEIGHT GAIN
MULTI-RING COMPOUNDS FOR REGULATING GUT MOTILITY, FOOD INTAKE, AND WEIGHT GAIN
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机译:调节肠胃蠕动,食物摄入和体重增加的多环化合物
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摘要
Multi-ring organic compounds that regulate gut motor activity, signal satiety, and reduce food intake in an individual are described Such compounds are useful to regulate food consumption and to treat conditions of excessive weight gam and obesity. These compounds are trichothecanes or trichothecenes of Formula I: wherein x is a single or double bond and R1 and R2 are, independently, selected from the group consisting of a branched or unbranched C1 to C6 alkyl group, a branched or unbranched C3 to C6 alkenyl group, a cyclic saturated C3-C6 ring, a monounsaturated C4-C6 ring, an optionally substituted aryl group, and a 5 or 6-membered heteroaromatic ring
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