METHODS FOR PRODUCING FUNCTIONAL ANTIGEN PRESENTING DENTRITIC CELLS USING BIODEGRADABLE MICROPARTICLES FOR DELIVERY OF ANTIGENIC MATERIALS

摘要

Methods are provided for producing functional antigen presenting dendritic cells. The dendritic cells are produced by treating an extracorporeal quantity of a subject’s blood to induce differentiation of blood monocytes into dendritic cells. The dendritic cells may be exposed to cellular material encapsulated within a biodegradable polymer material to produce the antigen presenting dendritic cells.