NEW METHOD FOR DOPAMINE MEASUREMENT AND DIAGNOSES AND FOLLOWING UP OF PSYCHOSIS

摘要

This invention relates to a new rapid and economical spectrophotometric method was applied for microdetermination of dopamine in pharmaceutical preparations and in urine samples of psychotic patients e.g. schizophrenic patients. This procedure depends on the formation of coloured complex between dopamine, copper sulfate and 4­aminoantipyrine under selected optimum conditions. The proposed procedure can be applied (1) to control the quantity of dopamine in pharmaceutical preparations (2) with psychiatric physician, which allows them to (a) detection the psychosis early which help in treatment and prevention of the disease e.g. screen study (b) diagnose of the disease (c) follow up the schizophrenic patients, (d) to control the dose of treatment and (f) prevention of relapse in patients on anti-psychotic drugs or with history of the disease.