首页> 外国专利> USE OF VITAMIN D RECEPTOR ACTIVATORS OR VITAMIN D ANALOGS TO TREAT CARDIOVASCULAR DISEASE

USE OF VITAMIN D RECEPTOR ACTIVATORS OR VITAMIN D ANALOGS TO TREAT CARDIOVASCULAR DISEASE

机译:使用维生素D受体激活剂或维生素D类似物治疗心血管疾病

摘要

Disclosed are pharmaceutical compositions containing Vitamin D receptor activators or Vitamin D analogs to treat, prevent or inhibit vascular disease among other conditions. The pharmaceutical compositions may also include ACE inhibitors or other agents. Also disclosed are methods of reducing PAI-1 expression by administering effective amounts of Vitamin D receptor activators or Vitamin D analogs to a mammal in need thereof. Additionally disclosed are methods of preventing, inhibiting or treating thrombosis in a mammal in need of such prevention, inhibition or treatment comprising administering effective amounts of Vitamin D receptor activators or Vitamin D analogs to the mammal.
机译:公开了包含维生素D受体活化剂或维生素D类似物以治疗,预防或抑制血管疾病等的药物组合物。药物组合物还可包含ACE抑制剂或其他试剂。还公开了通过向需要其的哺乳动物施用有效量的维生素D受体激活剂或维生素D类似物来减少PAI-1表达的方法。另外公开了在需要这种预防,抑制或治疗的哺乳动物中预防,抑制或治疗血栓形成的方法,包括向哺乳动物施用有效量的维生素D受体活化剂或维生素D类似物。

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