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DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH NUCLEAR RECEPTOR SUBFAMILY 3, GROUP C, MEMBER 2 (NR3C2)
DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH NUCLEAR RECEPTOR SUBFAMILY 3, GROUP C, MEMBER 2 (NR3C2)
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机译:与C组成员2的核受体子家族3相关的疾病的诊断和治疗(NR3C2)
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摘要
The invention provides a human NR3C2 which is associated with the cardiovascular diseases, infections, cancer, dermatological diseases, endocrinological diseases, metabolic diseases, inflammation, gastroenterological diseases, hematological diseases, respiratory diseases, muscle skeleton diseases, neurological diseases, urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, infections, cancer, dermatological diseases, endocrinological diseases, metabolic diseases, inflammation, gastroenterological diseases, hematological diseases, respiratory diseases, muscle skeleton diseases, neurological diseases, urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of NR3C2 as well as pharmaceutical compositions comprising such compounds.
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