STATIONARY PHASE ANTIBODY ARRAYS FOR TRACE PROTEIN ANALYSIS

摘要

The present invention relates to the identification of trace proteins and biomarkers, e.g., TH-1/TH-2, cytokines, matrix metalloproteases and angiogenic modulators in tear fluids. The present invention provides an antibody-based stationary phase array assay for simultaneously identifying, detecting and characterizing the distribution of a wide range of bioactive trace proteins in a tear fluid sample. A method for simultaneously identifying trace proteins in a biological fluid sample using a highly sensitive antibody-array assay is provided. The present invention also provides methods and kits for treating, preventing, and diagnosing ocular diseases, disorders or pathological conditions.